B-vac: A Robust Software Package For Bacterial Vaccine Design
A standalone, offline reverse vaccinology pipeline that screens bacterial proteomes to identify potential vaccine candidates — combining localization, non-host homology, virulence factor, and epitope mapping analysis in one user-friendly interface, with no internet connection or coding required.
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Localization
Flags surface-exposed and secreted proteins accessible to the host immune system.
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Non-Host Homologs
Filters out proteins similar to host sequences to reduce autoimmunity risk.
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Virulence Factors
Matches candidates against a curated database of known bacterial virulence factors.
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Epitope Mapping
Predicts B-cell and T-cell (CD4+/CD8+) epitopes for immunogenicity assessment.
Setup Information
VERSION
v1.0
CATEGORY
Reverse vaccinology / bacterial vaccine design
PLATFORM
Windows & Linux (standalone, Python-based)
INTERNET
Not Required
LICENSE
Apache License 2.0
B-vac's Publication
Cite B-vac when you use it in your research